Sodium Iodide → 5-(N,N-Dimethylthiocarbamoyl)thio-4-methyl-2-phenyl-4-isothiazolin-3-one

HRID 1105880

反応式

HRID 1105880 の反応式
Cl[C:2]1[S:6][N:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:4](=[O:13])[C:3]=1[CH3:14].[CH3:15][N:16]([CH3:20])[C:17](=[S:19])[SH:18].[Na].[I-].[Na+]>C(O)C>[CH3:15][N:16]([CH3:20])[C:17]([S:19][C:2]1[S:6][N:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:4](=[O:13])[C:3]=1[CH3:14])=[S:18]

参加物

6

反応物 4

HCID 5238Sodium IodideHCID 6599Dimethyldithiocarbamic acidHCID 5360545SodiumHCID 198761675-chloro-4-methyl-2-phenylisothiazol-3(2H)-one

生成物 1

HCID 128527285-(N,N-Dimethylthiocarbamoyl)thio-4-methyl-2-phenyl-4-isothiazolin-3-one

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

To a solution of 4.51 g. (0.02 mole) of 5-chloro-4-methyl-2-phenyl-4-isothiazolin-3-one in 30 ml of warm ethanol was added a solution of 3.58 g. (0.02 mole) of N,N-dimethyldithiocarbamic acid, sodium salt dihydrate in 20 ml of ethanol followed by 0.1 g. of sodium iodide. The mixture was stirred several hours, cooled and filtered. The solid was triturated with water and dried to give 5.3 g. (88%) of the named product, mp 158°-160°.

後処理

  1. temperaturecooled
  2. filtrationfiltered
  3. customThe solid was triturated with water
  4. customdried
  5. customto give 5.3 g

出典と根拠

ORDレコード
ord-14fd87cf8fe5449984c02e859ec68e5d
出典データセット
uspto-grants-1982_01
特許番号
US04310590

関連ノート

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