Chloride → 3-Benzyloxycarbonylamino-3-(1,1-difluoro-2-hydroxyethyl)pyrrolidine-1-carboxylic acid tert-butyl ester
反応式
[BH4-:32].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]([C:13]([CH:14]=[CH2:15])([F:16])[F:17])([NH:18][C:19](=[O:20])[O:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:11][CH2:12]1.[C:34](=[O:35])([OH:36])[O-:37].[CH3:41][OH:42].[CH:43]([Cl:44])([Cl:45])[Cl:46].[Cl-:40].[Na+:33].[Na+:38].[Na+:39].[O-:29][O+:30]=[O:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]([C:13]([CH2:14][OH:29])([F:16])[F:17])([NH:18][C:19](=[O:20])[O:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:11][CH2:12]1
