Formaldehyde → Benzenamine, 2,6-diethyl-N-methylene-

HRID 1283715ノート

反応式

HRID 1283715 の反応式
[CH2:1]([C:3]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][CH3:11])[C:4]=1[NH2:5])[CH3:2].C=O.[CH3:14]N(C)C.CCCCCCC>O>[CH2:14]=[N:5][C:4]1[C:6]([CH2:10][CH3:11])=[CH:7][CH:8]=[CH:9][C:3]=1[CH2:1][CH3:2]

参加物

6

反応物 4

HCID 712FormaldehydeHCID 1146TrimethylamineHCID 8900HeptaneHCID 113692,6-Diethylaniline

生成物 1

HCID 93179Benzenamine, 2,6-diethyl-N-methylene-

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

2,6-Diethylaniline (149.2 grams; 1.0 mole), paraformaldehyde (40 grams), a 25% solution of trimethylamine (1.7 grams) and heptane were charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser connected to a Dean-Stark trap. The reaction mixture was heated and the water formed removed by azeotropic distillation. When no more water could be removed, the reaction mixture was stripped of solvent and distilled to yield the desired product N-methylene-2,6-diethylaniline as a colorless oil having a boiling point of 65°C.

後処理

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperatureThe reaction mixture was heated
  4. customremoved by azeotropic distillation
  5. customWhen no more water could be removed
  6. distillationdistilled

出典と根拠

ORDレコード
ord-a26446e271234d7e90fffaa1f747d90e
出典データセット
uspto-grants-1976_08
特許番号
US03976471

反応ノート

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