Diisopropylethylamine → 4-Chloro-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid {2-methyl-5-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-benzoylamino]-phenyl}-amide

反応式

[CH:1]1[C:5]2[C:6]([Cl:10])=[N:7][CH:8]=[N:9][C:4]=2[NH:3][CH:2]=1.ClC(Cl)(O[C:15](=[O:21])OC(Cl)(Cl)Cl)Cl.CCN(C(C)C)C(C)C.[NH2:32][C:33]1[CH:34]=[C:35]([NH:40][C:41](=[O:58])[C:42]2[CH:47]=[C:46]([C:48]([F:51])([F:50])[F:49])[CH:45]=[C:44]([N:52]3[CH:56]=[C:55]([CH3:57])[N:54]=[CH:53]3)[CH:43]=2)[CH:36]=[CH:37][C:38]=1[CH3:39]>C1COCC1>[CH3:39][C:38]1[CH:37]=[CH:36][C:35]([NH:40][C:41](=[O:58])[C:42]2[CH:47]=[C:46]([C:48]([F:49])([F:50])[F:51])[CH:45]=[C:44]([N:52]3[CH:56]=[C:55]([CH3:57])[N:54]=[CH:53]3)[CH:43]=2)=[CH:34][C:33]=1[NH:32][C:15]([N:3]1[C:4]2[N:9]=[CH:8][N:7]=[C:6]([Cl:10])[C:5]=2[CH:1]=[CH:2]1)=[O:21]