2-Methoxypyrimidine-5-boronic acid → 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(6-(2-methoxypyrimidin-5-yl)-5-methylpyridin-2-yl)cyclopropanecarboxamide
反応式
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6](B(O)O)=[CH:5][N:4]=1.Cl[C:13]1[N:18]=[C:17]([NH:19][C:20]([C:22]2([C:25]3[CH:35]=[CH:34][C:28]4[O:29][C:30]([F:33])([F:32])[O:31][C:27]=4[CH:26]=3)[CH2:24][CH2:23]2)=[O:21])[CH:16]=[CH:15][C:14]=1[CH3:36]>COCCOC.C([O-])([O-])=O.[Na+].[Na+].C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[F:33][C:30]1([F:32])[O:29][C:28]2[CH:34]=[CH:35][C:25]([C:22]3([C:20]([NH:19][C:17]4[CH:16]=[CH:15][C:14]([CH3:36])=[C:13]([C:6]5[CH:5]=[N:4][C:3]([O:2][CH3:1])=[N:8][CH:7]=5)[N:18]=4)=[O:21])[CH2:24][CH2:23]3)=[CH:26][C:27]=2[O:31]1参加物
6
