N-Benzoylbenzylamine → N-benzyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

HRID 1491070ノート

反応式

HRID 1491070 の反応式
O=C(NCc1ccccc1)c1ccccc1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].[Ir].[Ir].c1ccc(-c2ccccn2)nc1>CC1(C)OB(c2ccccc2C(=O)NCc2ccccc2)OC1(C)C

参加物

6

反応物 1

HCID 73878N-Benzoylbenzylamine

生成物 1

HCID 172840361N-benzyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide収率 0%

試薬・触媒・溶媒 4

HCID 14742,2'-Bipyridine試薬HCID 2733548Bis(pinacolato)diborane試薬HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium触媒HCID 8028Tetrahydrofuran溶媒

反応条件

温度
60 °C

実験手順

Isolated by chromatography using deactivated silica gel and ethyl acetate and petroleum ether (10:1 to 1:1) as the eluent.

出典と根拠

ORDレコード
ord-a44cd281971b4c1a97b5dbb346e75a63
出典データセット
Borylation dataset from Roche

反応ノート

読み込み中…