反応式
[C:1]([OH:12])(=[O:11])[C:2]1[CH:10]=[C:8]([OH:9])[C:6]([OH:7])=[C:4]([OH:5])[CH:3]=1.C(O[C:17](=[O:19])[CH3:18])(=O)C.[C:20](Cl)(=[O:22])[CH3:21].[OH-].[Na+].[C:26]([O-:29])([O-])=O.[Na+].[Na+].N1C=CC=C[CH:33]=1>>[C:20]([O:5][C:4]1[CH:3]=[C:2]([CH:10]=[C:8]([O:9][C:17](=[O:19])[CH3:18])[C:6]=1[O:7][C:26](=[O:29])[CH3:33])[C:1]([OH:12])=[O:11])(=[O:22])[CH3:21]参加物
7
実験手順
Gallic acid is reacted with acetic anhydride or acetic chloride in the presence of bases, such as NaOH (J. Chem. Soc., 2495 (1931)), Na2CO3, or pyridine, to form 3,4,5-triacetoxybenzoic acid, which is then treated with thionyl chloride or phosphorus trichloride to form the corresponding acid chloride. This 3,4,5-triacetoxybenzoic acid chloride is reacted with a suitable amine compound in the presence of bases, such as pyridine and triethylamine, and thereafter, treated with sodium acetate, sodium hydroxide, hydrochloric acid or the like in methanol or ethanol to form the desired gallic acid amide.
出典と根拠
- ORDレコード
- ord-44724885dbf34238a40fac2f03e152cc
- 出典データセット
- uspto-grants-1984_10
- 特許番号
- US04474874
関連ノート
読み込み中…