Ethambutol Hydrochloride → Ethambutol

HRID 1643530

反応式

HRID 1643530 の反応式
[CH3:1][CH2:2][C@H:3]([NH:6][CH2:7][CH2:8][NH:9][C@H:10]([CH2:13][OH:14])[CH2:11][CH3:12])[CH2:4][OH:5].Cl.Cl>C(=O)([O-])[O-].[Na+].[Na+].[OH-].[Na+]>[CH3:12][CH2:11][C@H:10]([NH:9][CH2:8][CH2:7][NH:6][C@H:3]([CH2:4][OH:5])[CH2:2][CH3:1])[CH2:13][OH:14]

参加物

4

反応物 1

HCID 14051Ethambutol Hydrochloride3 回

生成物 1

HCID 14052Ethambutol

試薬・触媒・溶媒 2

HCID 10340Sodium Carbonate溶媒HCID 14798Sodium Hydroxide溶媒

実験手順

Ethambutol Dihydrochloride (ETB) is obtained from MP Biomedicals (Aurora, Ohio). ETB (7 grams) are dissolved in 100 mL of a saturated solution of sodium carbonate in 5M NaOH. The solution is stirred for 10 minutes and the free based ETB is extracted with three volumes of chloroform. The solution is dried over sodium sulfate. After filtration, the chloroform is removed by rotary evaporation. Ethambutol is represented in the structure below (a).

後処理

  1. extractionis extracted with three volumes of chloroform
  2. dry with materialThe solution is dried over sodium sulfate
  3. filtrationAfter filtration
  4. customthe chloroform is removed by rotary evaporation

出典と根拠

ORDレコード
ord-bc6a8db3687a4cab96373542461f07a9
出典データセット
uspto-grants-2012_02
特許番号
US08119840B2

関連ノート

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