Methyl iodide → 2-Cyclopentyl-2-methyl-5-methylthio-6,7-dichloro-1-indanone

HRID 1679738ノート

反応式

HRID 1679738 の反応式
[CH:1]1([CH:6]2[CH2:14][C:13]3[C:8](=[C:9]([Cl:18])[C:10]([Cl:17])=[C:11]([S:15][CH3:16])[CH:12]=3)[C:7]2=[O:19])[CH2:5][CH2:4][CH2:3][CH2:2]1.[H-].[Na+].[CH3:22]I>COCCOC>[CH:1]1([C:6]2([CH3:22])[CH2:14][C:13]3[C:8](=[C:9]([Cl:18])[C:10]([Cl:17])=[C:11]([S:15][CH3:16])[CH:12]=3)[C:7]2=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5]1

参加物

5

反応物 3

HCID 6328Methyl iodideHCID 24758Sodium hydrideHCID 203584542-Cyclopentyl-5-methylthio-6,7-dichloro-1-indanone

生成物 1

HCID 203584612-Cyclopentyl-2-methyl-5-methylthio-6,7-dichloro-1-indanone

試薬・触媒・溶媒 1

HCID 80711,2-Dimethoxyethane溶媒

実験手順

2-Cyclopentyl-2-methyl-5-methylthio-6,7-dichloro-1-indanone is prepared following substantially the same procedure described in Example 10, Step D, using the following substances: 2-cyclopentyl-5-methylthio-6,7-dichloro-1-indanone (7.9 g., 0.025 mole), 1,2-dimethoxyethane (200 ml.), sodium hydride (660 mg., 0.0275 mole) and methyl iodide (7.5 ml.).

出典と根拠

ORDレコード
ord-888de91ad6ac46f393e0d0be5399a80d
出典データセット
uspto-grants-1978_03
特許番号
US04081554

反応ノート

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