Acetic Acid → Adipic Acid

HRID 1744005

反応式

HRID 1744005 の反応式
[C:1]1(=[O:7])[CH2:6][CH2:5][CH2:4]CC1.[N+]([O-])(O)=O.[O:12]=O.[C:14]([OH:17])(=[O:16])[CH3:15]>[N+]([O-])([O-])=O.[Mn+2].[N+]([O-])([O-])=O.[N+]([O-])([O-])=O.[Co+2].[N+]([O-])([O-])=O>[C:1]([OH:7])(=[O:12])[CH2:6][CH2:5][CH2:4][CH2:15][C:14]([OH:17])=[O:16]

参加物

7

反応物 4

HCID 176Acetic AcidHCID 944Nitric AcidHCID 977OxygenHCID 7967Cyclohexanone

生成物 1

HCID 196Adipic Acid

試薬・触媒・溶媒 2

HCID 25000Cobalt dinitrate触媒HCID 61511Manganese nitrate触媒

実験手順

A solution containing 25 mmol of cyclohexanone, 0.5 mmol of manganese(II) nitrate, 0.5 mmol of cobalt(II) nitrate and 1.5 mmol of nitric acid in 25 ml of acetic acid was stirred for 5 h at 40° C. in an oxygen atmosphere under ambient pressure. Subsequently, the acetic acid was distilled off. The residue was found to consist mainly of adipic acid with some glutaric acid and a small amount of unreacted starting material. The conversion of cyclo-hexanone was found to be 97.5%, the selectivity of the oxidation to adipic acid being 93.4%.

後処理

  1. distillationSubsequently, the acetic acid was distilled off

出典と根拠

ORDレコード
ord-ea8b88fa6ef14293914a9ca4eb3c2d0d
出典データセット
uspto-grants-2006_03
特許番号
US07012155B2

関連ノート

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