1,1'-Carbonyldiimidazole → hexahydroimidazo[1,5-a]pyridin-3(2H)-one

HRID 1775508

反応式

HRID 1775508 の反応式
C1N=CN([C:6](N2C=NC=C2)=[O:7])C=1.[NH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH:14]1[CH2:19][NH2:20]>C(Cl)Cl>[CH2:19]1[CH:14]2[CH2:15][CH2:16][CH2:17][CH2:18][N:13]2[C:6](=[O:7])[NH:20]1

参加物

4

反応物 2

HCID 682631,1'-CarbonyldiimidazoleHCID 90865Piperidine-2-methylamine

生成物 1

HCID 47002315hexahydroimidazo[1,5-a]pyridin-3(2H)-one

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A solution of CDI (830 mg, 5.1 mmol) and piperidin-2-ylmethanamine (520 mg, 4.6 mmol) in DCM (20 mL) was stirred at room temperature overnight. After the solvent was removed, the residue was directly used for the next step without further purification.

後処理

  1. customAfter the solvent was removed
  2. customthe residue was directly used for the next step without further purification

出典と根拠

ORDレコード
ord-619ee6518b044e9c8f2128490bba4c10
出典データセット
uspto-grants-2016_02
特許番号
US09260452B2

関連ノート

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