The title compound was prepared following the procedure as described for Example-177 using 7-[(2,6-dichlorophenyl)amino]-2-methyl-8H-imidazo[4,5-e][1,3]benzoxazole-4-carboxylic acid (Intermediate-55, 0.100 g, 0.276 mmol), benzene (4 mL), thionyl chloride (5.0 mL), 4-bromo aniline (0.142 g, 0.828 mmol), THF (5.0 mL) and 60% NaH (0.033 g, 0.825 mmol). The obtained product was further purified by column chromatography on neutral alumina eluting with 1.5-2.0% MeOH:DCM to afford 0.022 g of the desired product. 1HNMR (DMSO-d6): δ 2.70 (s, 3H), 6.54 (s, 1H), 6.67 (d, J=8.4 Hz, 1H), 6.83 (s, 1H), 6.98 (d, J=8.1 Hz, 1H), 7.12-7.26 (m, 2H), 7.33-7.38 (m, 2H), 8.61 (s, 1H), 9.04 (s, 1H); MS [M+H]+: 532.47.
