3-Isobutyl-1-methylxanthine → N7-bromoehtyl 3-isobutyl-1-methylxanthine
反応式
[CH2:1]([N:5]1[C:13]2[N:12]=[CH:11][NH:10][C:9]=2[C:8](=[O:14])[N:7]([CH3:15])[C:6]1=[O:16])[CH:2]([CH3:4])[CH3:3].[Br:17][CH2:18][CH2:19]N.[OH-].[Na+]>CO>[Br:17][CH2:18][CH2:19][N:10]1[C:9]2[C:8](=[O:14])[N:7]([CH3:15])[C:6](=[O:16])[N:5]([CH2:1][CH:2]([CH3:4])[CH3:3])[C:13]=2[N:12]=[CH:11]1参加物
5
実験手順
The process of preparing the compound of formula I comprises the steps of dissolving 3-isobutyl-1-methylxanthine (IBMX) into methanol and stirring with 2-bromoethylamine upon a mantle heater, reacting this mixture with NaOH and then recrystallizing this mixture with methanol to obtain N7-bromoehtyl 3-isobutyl-1-methylxanthine.
後処理
- customThe process of preparing the compound of formula I
- customrecrystallizing this mixture with methanol
出典と根拠
- ORDレコード
- ord-2844dad69a4b4a888264a6e4aab7ae9d
- 出典データセット
- uspto-grants-2009_06
- 特許番号
- US07550468B2
反応ノート
読み込み中…