Trifluoroacetic acid → (3RS,4SR)-1-Benzyl-4-(3,4-difluoro-phenyl)-pyrrolidine-3-carboxylic acid

HRID 199541ノート

反応式

[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:1][O:2][CH2:3][N:4]([CH2:5][Si:6]([CH3:7])([CH3:8])[CH3:9])[CH2:10][c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1.[F:17][c:18]1[cH:19][c:20]([CH:25]=[CH:26][C:27](=[O:28])[OH:29])[cH:21][cH:22][c:23]1[F:24].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[CH2:3]1[N:4]([CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:5][CH:26]([C:27](=[O:28])[OH:29])[CH:25]1[c:20]1[cH:19][c:18]([F:17])[c:23]([F:24])[cH:22][cH:21]1