2-Chloro-4,6-diphenyl-1,3,5-triazine → 2-Azido-4,6-diphenyl-s-triazine

HRID 2050234

反応式

HRID 2050234 の反応式
Cl[C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:3]=1.[N-:20]=[N+:21]=[N-:22].[Na+].[N-]=[N+]=[N-].[Li+]>C(#N)C>[N:20]([C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:3]=1)=[N+:21]=[N-:22]

参加物

5

反応物 3

HCID 196982-Chloro-4,6-diphenyl-1,3,5-triazineHCID 33557Sodium AzideHCID 88163Lithium azide

生成物 1

HCID 6236432-Azido-4,6-diphenyl-s-triazine収率 88%

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

A suspension of 2-chloro-4,6-diphenyl-s-triazine (30 g, 0.112 mol), sodium azide (12.86 g, 0.199 mol) and lithium azide (1.25 g, 0.025 mol) in acetonitrile (550 ml) was stirred at room temperature for 11 days. After filtration, the filtrate on evaporation yielded 6.9 g of 2-azido-4,6-diphenyl-s-triazine, mp 115°-117° C. The residue on extraction with hot heptane, followed by crystallization from heptane, gave an additional 20 g quantity having a mp of 114°-116° C. bringing the total yield of 2-azido-4,6-diphenyl-s-triazine to 26.9 g (88% yield). The melting point and infrared spectrum were identical with that of an authentic sample.

後処理

  1. filtrationAfter filtration
  2. customthe filtrate on evaporation

出典と根拠

ORDレコード
ord-d13009c8aded4081a490a33541fc3944
出典データセット
uspto-grants-1980_04
特許番号
US04200721

関連ノート

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