Pyridine → 5,5-Dimethyl-3-oxocyclohex-1-en-1-yl acetate
反応式
[C:1](Cl)(=[O:3])[CH3:2].[CH3:5][C:6]1([CH3:14])[CH2:11][C:10](=[O:12])[CH2:9][C:8](=[O:13])[CH2:7]1.N1C=CC=CC=1>C(Cl)(Cl)Cl>[C:1]([O:12][C:10]1[CH2:11][C:6]([CH3:14])([CH3:5])[CH2:7][C:8](=[O:13])[CH:9]=1)(=[O:3])[CH3:2]参加物
5
実験手順
Acetyl chloride (1.1 ml, 15.65 mmol) was added to a stirred solution of 5,5-dimethyl-cyclohexane-1,3-dione (2.1 g, 14.23 mmol) and pyridine (1.14 ml), in chloroform (50 ml). The mixture was stirred at room temperature for about 1.5 hours, then washed with water, 0.1N HCl, saturated aqueous sodium hydrogen carbonate and water. The organic phase was dried over sodium sulfate and evaporated to dryness to give 2.5 g (96%) of the title compound as a colourless oil, which was used as such without any further purification.
後処理
- washwashed with water, 0.1N HCl, saturated aqueous sodium hydrogen carbonate and water
- dry with materialThe organic phase was dried over sodium sulfate
- customevaporated to dryness
出典と根拠
- ORDレコード
- ord-efaf1dabc53c4df7a35d7d91a9f4ec50
- 出典データセット
- uspto-grants-2004_04
- 特許番号
- US06716856B1
反応ノート
読み込み中…