Water → Oxirane, 2-((4-chlorophenyl)methyl)-

HRID 2107064

反応式

HRID 2107064 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]=[CH2:10])=[CH:4][CH:3]=1.ClC1C=CC=C(C(OO)=[O:19])C=1.O>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]2[O:19][CH2:10]2)=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 962WaterHCID 70297m-Chloroperbenzoic acidHCID 110190641-Allyl-4-chlorobenzene

生成物 1

HCID 148012Oxirane, 2-((4-chlorophenyl)methyl)-

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

To a solution of 3-(4-chlorophenyl)prop-1-ene (9.0 g) in chloroform (100 ml) was added portionwise metachloroperbenzoic acid (12.2 g), and the solution was stirred for 5 h at room temperature. The mixture was poured into water, the water layer was separated and the organic layer washed successively with sodium bicaronate, sodium sulphite and water. After drying, evaporation of the solvent gave 1-(4-chlorophenyl)-2,3-epoxypropane as a pale yellow oil. (9.51 g). NMR in CDCl3 :

後処理

  1. customthe water layer was separated
  2. washthe organic layer washed successively with sodium bicaronate, sodium sulphite and water
  3. customAfter drying
  4. customevaporation of the solvent

出典と根拠

ORDレコード
ord-b212209cb977459caa6ffe79f2a61af2
出典データセット
uspto-grants-1990_06
特許番号
US04933357

関連ノート

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