Hydrochloric Acid → 2-Propenoic acid, 3-phenyl-

HRID 22097

反応式

HRID 22097 の反応式
[C:1]([O:14]C)(=[O:13])/[CH:2]=[CH:3]/[C:4]1[CH:12]=[CH:11][C:8](OC)=[C:6](O)[CH:5]=1.[H-].[Na+].C1OC1CO.Cl>CS(C)=O>[C:1]([OH:14])(=[O:13])[CH:2]=[CH:3][C:4]1[CH:5]=[CH:6][CH:8]=[CH:11][CH:12]=1

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 11164GlycidolHCID 24758Sodium hydrideHCID 6439893Methyl isoferulate

生成物 1

HCID 87842-Propenoic acid, 3-phenyl-

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

実験手順

3 g of methyl isoferulate was dissolved in 600 ml of DMSO, and 370 mg of sodium hydride was added. The system was heated to 90° C. under N2 gas flow and 7 g of glycidol was added gradually. Heating and agitation was carried out for 0.5 hours. The system was cooled, neutralized by adding hydrochloric acid, solvent was removed and adduct of cinnamic acid and glycerin was obtained.

後処理

  1. additionwas added gradually
  2. temperatureHeating
  3. temperatureThe system was cooled
  4. customwas removed

出典と根拠

ORDレコード
ord-f297ae3acb9542e7bf85a53dda6a37d2
出典データセット
uspto-grants-1995_06
特許番号
US05426210

関連ノート

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