3-Methyl-2-buten-1-OL → 3,3-Dimethylallylglycidyl ether

To a solution of 3,3-dimethylallyl alcohol (17.3 g, 20.5 mL, 0.2 mol) in dry tetrahydrofuran (THF) (200 mL) was added sodium hydride (4.8 g, 0.2 mol) in portions and the mixture was stirred at room temperature for 1 hr. Epibromohydrin (27.4 g, 17.12 mL, 0.2 mol) was added dropwise and the reaction mixture was stirred at room temperature for 24 hrs. THF was removed on a rotary evaporator and the residue was taken up in ether and filtered. The ether solution was concentrated on a rotary evaporator and the brown oil obtained was distilled under vacuum.

1. stirringthe reaction mixture was stirred at room temperature for 24 hrs
2. customTHF was removed on a rotary evaporator
3. filtrationfiltered
4. concentrationThe ether solution was concentrated on a rotary evaporator
5. customthe brown oil obtained
6. distillationwas distilled under vacuum

ORDレコード

ord-85453916f8e0490a9eb28b355a5f45c6

出典データセット

uspto-grants-1997_08

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US05656254