Methyl Methanesulfonate → 2-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyltrimethylammonium mesylate

HRID 231263

反応式

HRID 231263 の反応式
[CH3:1][O:2][CH:3]([CH2:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:4][S:5]([CH2:8][CH2:9][N:10]([CH3:12])[CH3:11])(=[O:7])=[O:6].[CH3:33][S:34]([O:37]C)(=[O:36])=[O:35]>C(Cl)(Cl)Cl>[S:34]([O-:37])(=[O:36])(=[O:35])[CH3:33].[CH3:1][O:2][CH:3]([CH2:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:4][S:5]([CH2:8][CH2:9][N+:10]([CH3:33])([CH3:12])[CH3:11])(=[O:6])=[O:7]

参加物

4

反応物 2

HCID 4156Methyl MethanesulfonateHCID 144982652-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyldimethylamine

生成物 1

HCID 144982462-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyltrimethylammonium mesylate収率 70.6%

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

反応条件

温度
70 °C

実験手順

In 10 ml of chloroform are dissolved 0.48 g of 2-[(2-methoxy-3-octadecyloxypropyl)sulfonyl]ethyldimethylamine and 1 g of methyl methanesulfonate and the solution is stirred at 70° C. for 5 hours. Then the reaction mixture is concentrated under reduced pressure and the residue is crystallized from chloroform and ether to give 417 mg of the captioned compound.

後処理

  1. concentrationThen the reaction mixture is concentrated under reduced pressure
  2. customthe residue is crystallized from chloroform and ether

出典と根拠

ORDレコード
ord-1c6f273932834c8c827785532613c3dc
出典データセット
uspto-grants-1989_07
特許番号
US04845219

関連ノート

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