Glycylglycine → Methacryloylglycylglycine

HRID 2380690

反応式

HRID 2380690 の反応式
[NH2:1][CH2:2][C:3]([NH:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4].[C:10](Cl)(=[O:14])[C:11]([CH3:13])=[CH2:12]>O>[C:10]([NH:1][CH2:2][C:3]([NH:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4])(=[O:14])[C:11]([CH3:13])=[CH2:12]

参加物

4

反応物 2

HCID 11163GlycylglycineHCID 13528Methacryloyl chloride

生成物 1

HCID 10241886Methacryloylglycylglycine収率 75%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Using Example 1, glycylglycine was reacted with methacryloyl chloride in water at -10° C. After adjustment to a pH of 3, the white slurry was washed with ethanol to remove sodium chloride and water. The product was dried at 80° C. to obtain a good yield (>75%) product with a melting point of 200°-201° C.

後処理

  1. washAfter adjustment to a pH of 3, the white slurry was washed with ethanol
  2. customto remove sodium chloride and water
  3. customThe product was dried at 80° C.
  4. customto obtain

出典と根拠

ORDレコード
ord-86af07b8d12f4df8a95f65f97388eba5
出典データセット
uspto-grants-1994_11
特許番号
US05369142

関連ノート

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