Hydrochloric Acid → 4'-Hydroxybiphenyl 4-octyloxybenzoate

HRID 248774

反応式

HRID 248774 の反応式
[CH:1]1[C:6]([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)=[CH:5][CH:4]=[C:3](O)[CH:2]=1.C(OC1C=CC(C(Cl)=O)=CC=1)CCCCCCC.[CH2:33]([O:41][C:42]1[CH:50]=[CH:49][C:45]([C:46]([OH:48])=[O:47])=[CH:44][CH:43]=1)[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].Cl>N1C=CC=CC=1>[CH2:33]([O:41][C:42]1[CH:43]=[CH:44][C:45]([C:46]([OH:48])=[O:47])=[CH:49][CH:50]=1)[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].[OH:13][C:10]1[CH:9]=[CH:8][C:7]([C:6]2[CH:1]=[CH:2][CH:3]=[CH:4][CH:5]=2)=[CH:12][CH:11]=1

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 71124,4'-DihydroxybiphenylHCID 172314-(Octyloxy)benzoic acidHCID 27602504-Octyloxybenzoyl chloride

生成物 1

HCID 677406704'-Hydroxybiphenyl 4-octyloxybenzoate収率 53%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

11.2 g (0.06 mol) of p,p'-biphenol and 5.4 g (0.02 mol) of 4-octyloxybenzoyl chloride derived from 4-octyloxybenzoic acid were dissolved in 100 ml of dried pyridine, which were stirred at room temperature for a night. After the completion of the reaction, the reaction mixture was added with 6 normal hydrochloric acid to adjust pH to not more than 1 and then the precipitate was taken out by filtration. Thus obtained precipitate was recrystallized from ethanol to obtain 4.4 g (yield: 53%) of a white crystal.

後処理

  1. customAfter the completion of the reaction
  2. filtrationthe precipitate was taken out by filtration
  3. customThus obtained precipitate was recrystallized from ethanol

出典と根拠

ORDレコード
ord-a17d1b3421094bbfb8e3d101338174fa
出典データセット
uspto-grants-1993_05
特許番号
US05211879

関連ノート

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