Isopropanol → HCID 21424687、化合物

HRID 258817

反応式

HRID 258817 の反応式
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1.[OH:12][CH2:13][CH2:14][N:15]([CH2:19][CH2:20][CH2:21][NH2:22])[CH2:16][CH2:17][OH:18].C(=O)([O-])[O-].[Na+].[Na+].C(O)(C)C>C(Cl)(Cl)Cl>[OH:18][CH2:17][CH2:16][N:15]([CH2:14][CH2:13][OH:12])[CH2:19][CH2:20][CH2:21][NH:22][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][CH:3]=1

参加物

6

反応物 4

HCID 3776IsopropanolHCID 10340Sodium CarbonateHCID 21088(3-Aminopropyl)diethanolamineHCID 691404-Chloroquinoline

生成物 1

HCID 21424687HCID 21424687、化合物

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

A mixture of 5.0 g. of 4-chloroquinoline, 7.2 g. of bis(2-hydroxyethyl)aminopropylamine, 3.0 g. of sodium carbonate and 25 ml. of isopropanol is heated in a pressure vessel at 150° C. for 17 hours. The resulting mixture is diluted with chloroform, filtered and purified by filtering over silica gel to obtain an oil of 4-[3-bis(2-hydroxyethyl)aminopropyl]amino-quinoline.

後処理

  1. additionA mixture of 5.0 g
  2. filtrationfiltered
  3. custompurified
  4. filtrationby filtering over silica gel

出典と根拠

ORDレコード
ord-ffe936cf2a1e425e9c83948efb67bf2b
出典データセット
uspto-grants-1977_07
特許番号
US04035367

関連ノート

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