Water → HCID 178511480、化合物
反応式
Cl[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH2:11][C:12]#[N:13])(=O)=[O:9])=[CH:4][CH:3]=1.[ClH:14].[NH2:15][OH:16].[OH2:17].C([O-])([O-])=O.[Na+].[Na+]>C(O)C>[Cl:14][C:2]1[CH:3]=[CH:4][C:5]([S:8]([CH2:11][C:12](=[NH:13])[NH:15][OH:16])(=[O:9])=[O:17])=[CH:6][CH:7]=1参加物
6
実験手順
50 g. (0.23 mole) of 4-chlorophenylsulfonylacetonitrile were dissolved in 1.5 liters of ethanol and 16 g. (0.23 mole) of hydroxylamine HCl in 150 ml. of water was added to this solution, followed by the addition of 14.4 g. (0.12 mole) of Na2CO3 in 150 ml. of water. This reaction mixture was stirred at room temperature overnight. 58 g. crude product were filtered off; this was recrystallized from about 2.5 liters of ethanol to give 40 g. of the product (70% yield).
後処理
- additionfollowed by the addition of 14.4 g
- filtrationcrude product were filtered off
- customthis was recrystallized from about 2.5 liters of ethanol
- customto give 40 g
出典と根拠
- ORDレコード
- ord-cfb04106ce044c1b82b83425a88a2633
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04148801
反応ノート
読み込み中…