Acetoacetanilide → HCID 178418293、化合物

HRID 2850

反応式

HRID 2850 の反応式
[C:1]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4].[OH-].[Na+].[Cl-].[C:17]1([N+:23]#[N:24])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>O>[C:8]1([NH:7][C:1](=[O:6])[C:2](=[N:24][NH:23][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:3](=[O:4])[CH3:5])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

参加物

5

反応物 3

HCID 7592AcetoacetanilideHCID 14798Sodium HydroxideHCID 60992Benzenediazonium chloride

生成物 1

HCID 178418293HCID 178418293、化合物収率 47.6%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

4.5 g (25.4 mmol) of acetoacetanilide, a solution of 3.46 g (89 mmol) of NaOH in 45 ml of water and 95 mmol of phenyldiazonium chloride were treated as described in preparation 8. The residue was crystallised from EtOH, yielding 3.4 g of the title compound. M.p.=96°-97° C.

後処理

  1. customas described in preparation 8
  2. customThe residue was crystallised from EtOH

出典と根拠

ORDレコード
ord-f388a24479e44c98bc290884466e1ad3
出典データセット
uspto-grants-1998_03
特許番号
US05731322

関連ノート

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