反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH3:9])=[CH:4][CH:3]=1.Cl.[NH2:12][OH:13].[OH-].[Na+].[Cl-].[Na+]>C(O)C.O>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[N:12][OH:13])[CH3:9])=[CH:4][CH:3]=1参加物
7
実験手順
To a mixture of 1-(4-amino-phenyl)-ethanone (2.75 g, 20.3 mmol) and hydroxylamine hydrochloride salt (2.1 g, 30.5 mmol) in ethanol (200 ml) was added sodium hydroxide (4.1 g, 101.7 mmol) in water (50 ml). After stirring for 18 hours, the mixture was treated with saturated aqueous sodium chloride solution (100 ml) and extracted with dichloromethane (200 ml). The organic extract was concentrated under reduced pressure to afford 1-(4-amino-phenyl)-ethanone-oxime (30% yield).
後処理
- extractionextracted with dichloromethane (200 ml)
- extractionThe organic extract
- concentrationwas concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-4d7aca234a664cbe99991eb96404e5e8
- 出典データセット
- uspto-grants-2008_09
- 特許番号
- US07419984B2
関連ノート
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