反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]([NH2:11])[CH3:10])[CH:6]=[CH:7][CH:8]=1.[C:12]([C:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=[CH:17][CH:16]=1)(=O)[CH3:13].C([BH3-])#N.[Na+]>CC(C)[O-].[Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-]>[C:15]1([CH:12]([NH:11][CH:9]([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=2)[CH3:10])[CH3:13])[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=[CH:17][CH:16]=1参加物
5
実験手順
In a similar fashion equal molar amounts of 1-(3-methoxyphenyl)ethylamine, 1′-acetonaphthone and 1.25 equivalents of titanium(IV) isopropoxide were mixed and the resulting intermediate imine was reduced with ethanolic sodium cyanoborohydride. Work-tip and chromatography yielded N-1-(1-naphthyl)ethyl-1-(3-methoxyphenyl)ethylamine, 6E, as a clear, colorless oil; m/z (rel. int.) 305 (M+, 10), 290 (30), 170 (43), 155 (100), 135 (69), 115 (9), 105 (15), 91 (14), 77 (18).
出典と根拠
- ORDレコード
- ord-07505d6320414ed987b337d92c06d97a
- 出典データセット
- uspto-grants-2001_04
- 特許番号
- US06211244B1
関連ノート
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