Sodium Carbonate → 5-Phenyl-2-picoline N-oxide
反応式
[C:1]1([C:7]2[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1C=C(Cl)C=C(C(OO)=[O:22])C=1.C([O-])([O-])=O.[Na+].[Na+]>C(Cl)Cl>[C:1]1([C:7]2[CH:8]=[N+:9]([O-:22])[C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1参加物
5
実験手順
A solution of 3-phenyl-6-methyl pyridine (2.36 g, 13.95 mmol), in CH2Cl2 (40 mL) at 0° C. was treated with MCPBA (3.58 g, 13.95 mmol) for 1 hour. Saturated aq. Na2CO3 (50 mL) was added and the reaction was extracted with CH2Cl2 (20 mL). The organic extracts were dried (MgSO4), and the solvent evaporated in vacuo to afford the title compound.
後処理
- extractionthe reaction was extracted with CH2Cl2 (20 mL)
- dry with materialThe organic extracts were dried (MgSO4)
- customthe solvent evaporated in vacuo
出典と根拠
- ORDレコード
- ord-05a8840426d74b2e8630c01407e52f00
- 出典データセット
- uspto-grants-1999_02
- 特許番号
- US05872136
反応ノート
読み込み中…