Sodium Carbonate → 5-Phenyl-2-picoline N-oxide

HRID 363196

反応式

HRID 363196 の反応式
[C:1]1([C:7]2[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1C=C(Cl)C=C(C(OO)=[O:22])C=1.C([O-])([O-])=O.[Na+].[Na+]>C(Cl)Cl>[C:1]1([C:7]2[CH:8]=[N+:9]([O-:22])[C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

5

反応物 3

HCID 10340Sodium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 767442-Methyl-5-phenylpyridine

生成物 1

HCID 149805285-Phenyl-2-picoline N-oxide

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A solution of 3-phenyl-6-methyl pyridine (2.36 g, 13.95 mmol), in CH2Cl2 (40 mL) at 0° C. was treated with MCPBA (3.58 g, 13.95 mmol) for 1 hour. Saturated aq. Na2CO3 (50 mL) was added and the reaction was extracted with CH2Cl2 (20 mL). The organic extracts were dried (MgSO4), and the solvent evaporated in vacuo to afford the title compound.

後処理

  1. extractionthe reaction was extracted with CH2Cl2 (20 mL)
  2. dry with materialThe organic extracts were dried (MgSO4)
  3. customthe solvent evaporated in vacuo

出典と根拠

ORDレコード
ord-05a8840426d74b2e8630c01407e52f00
出典データセット
uspto-grants-1999_02
特許番号
US05872136

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