Potassium Carbonate → 1-(2-Hydrazinylethyl)pyrrolidine

HRID 364182

反応式

HRID 364182 の反応式
O.[NH2:2][NH2:3].Cl.Cl[CH2:6][CH2:7][N:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1.C(=O)([O-])[O-].[K+].[K+].[OH-].[Na+]>O>[NH:2]([CH2:6][CH2:7][N:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1)[NH2:3]

参加物

6

反応物 4

HCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 816681-(2-Chloroethyl)pyrrolidine hydrochloride

生成物 1

HCID 30315561-(2-Hydrazinylethyl)pyrrolidine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 200 g of 85% hydrazine hydrate, 200 ml of water, 170 g of N-chloroethylpyrrolidine hydrochloride, and 70 g of potassium carbonate was boiled under reflux for seven hours. Sodium hydroxide (390 g) was added and the mixture was extracted with ether. The ethereal extract, dried and distilled, yielded the title compound, bp 107°-111° C. (18.5 mm).

後処理

  1. temperatureunder reflux for seven hours
  2. extractionthe mixture was extracted with ether
  3. extractionThe ethereal extract
  4. customdried
  5. distillationdistilled

出典と根拠

ORDレコード
ord-16204511989e437e8028f0fb62d2c3b9
出典データセット
uspto-grants-1986_08
特許番号
US04604390

関連ノート

読み込み中…