Heptafluorobutyryl Chloride → Heptafluorobutyraldehyde

HRID 36464

反応式

HRID 36464 の反応式
C([SiH](C(C)C)C(C)C)(C)C.[C:11]([C:15]([C:18]([C:21](Cl)=[O:22])([F:20])[F:19])([F:17])[F:16])([F:14])([F:13])[F:12]>[Pd]>[C:18]([CH:21]=[O:22])([C:15]([C:11]([F:12])([F:13])[F:14])([F:17])[F:16])([F:20])[F:19]

参加物

4

反応物 2

HCID 67810Heptafluorobutyryl ChlorideHCID 138754Silane, tris(1-methylethyl)-

生成物 1

HCID 67809Heptafluorobutyraldehyde収率 64.4%

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

反応条件

温度
0 °C

実験手順

A 3-necked round bottom flask fitted with dropping funnel, dry-ice condenser, and gas inlet was charged with 10% Pd/C(0.35 g) and cooled to 0° C. Triisopropylsilane (7.29 g, 46 mmol) was added, and CF3CF2CF2C(O)Cl (9.30 g, 40 mmol) was added dropwise over a 10 min period. The reactor was connected to a cold trap (-78° C.) while the mixture was stirred for 18 hr. Transfer from the trap and reaction vessel gave a total of 5.1 g (62%) of colorless liquid. 1H NMR (CD2Cl2): 9.62 (m). 19F NMR: -81.24 (t, J=8.3 Hz), -126.4 (quartet of doublets, Jq =8.3, Jd =3.2), -127.9 (s).

後処理

  1. customA 3-necked round bottom flask fitted
  2. customThe reactor was connected to a cold trap
  3. customTransfer from the trap and reaction vessel

出典と根拠

ORDレコード
ord-10a3cd1bb37642bd9b0560357400337e
出典データセット
uspto-grants-1995_05
特許番号
US05414140

関連ノート

読み込み中…