反応式
ClC1C([N+]([O-])=[O:9])=C(Cl)N=CN=1.[CH3:12][N:13]1[CH2:18][CH2:17][CH:16](NC)[CH2:15][CH2:14]1.[CH2:21]([C:23]1[NH:24][CH:25]=[CH:26][N:27]=1)[CH3:22].C1CCCCC=1.[C:34]([N:41]1[CH:45]=[CH:44][N:43]=[CH:42]1)([N:36]1C=[CH:39][N:38]=[CH:37]1)=O>[Pd].C(O)C>[CH2:21]([C:23]1[N:27]2[C:26]([C:42](=[O:9])[NH:43][C:44]3[C:37]([NH:38][CH2:39][CH:16]4[CH2:15][CH2:14][N:13]([CH3:12])[CH2:18][CH2:17]4)=[N:36][CH:34]=[N:41][C:45]=32)=[CH:25][N:24]=1)[CH3:22]参加物
8
反応物 5
生成物 1
試薬・触媒・溶媒 2
実験手順
Prepared by treatment of 4,6-dichloro-5-nitropyrimidine with 1-methyl-4-(methylamino)piperidine followed by reaction with 2-ethylimidazole, reduction with palladium on carbon and cyclohexene in refluxing ethanol, and cyclization with carbonyidiimidazole.
出典と根拠
- ORDレコード
- ord-3212f7b590b4430483b6c6024c3e6bfd
- 出典データセット
- uspto-grants-2000_02
- 特許番号
- US06025489
関連ノート
読み込み中…