Methyl iodide → (NZ)-N-[3-(4-chlorophenyl)-1,3-thiazolidin-2-ylidene]-3-methylimidazol-3-ium-1-carboxamide iodide

HRID 390699

反応式

HRID 390699 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:12][CH2:11][S:10]/[C:9]/2=[N:13]\[C:14]([N:16]2[CH:20]=[CH:19][N:18]=[CH:17]2)=[O:15])=[CH:4][CH:3]=1.[I:21][CH3:22]>C(#N)C>[I-:21].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH2:12][CH2:11][S:10]/[C:9]/2=[N:13]\[C:14]([N:16]2[CH:20]=[CH:19][N+:18]([CH3:22])=[CH:17]2)=[O:15])=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 87449094HCID 87449094、化合物

生成物 1

HCID 87447829(NZ)-N-[3-(4-chlorophenyl)-1,3-thiazolidin-2-ylidene]-3-methylimidazol-3-ium-1-carboxamide iodide

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

N-[(2Z)-3-(4-Chlorophenyl)-1,3-thiazolidin-2-ylidene]-1H-imidazole-1-carboxamide (320 mg, 1.043 mmol, Example 25A) was suspended in dry acetonitrile (5 mL), and then iodomethane (0.325 mL, 5.22 mmol) was added. The mixture stirred at room temperature. After four days, the solvent was evaporated to give the title product.

後処理

  1. customthe solvent was evaporated

出典と根拠

ORDレコード
ord-9fa71b9d1bd841759cde32862025345d
出典データセット
uspto-grants-2013_02
特許番号
US08383657B2

関連ノート

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