Methylamine → 4-(Methylamino)-3-nitrobenzoic acid

HRID 410716

反応式

HRID 410716 の反応式
F[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].[CH3:14][NH2:15]>C1COCC1>[CH3:14][NH:15][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12]

参加物

4

反応物 2

HCID 6329MethylamineHCID 679874-Fluoro-3-nitrobenzoic acid

生成物 1

HCID 2834754-(Methylamino)-3-nitrobenzoic acid

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

4-Methylamino-3-nitro-benzoic acid (825 mg) was prepared by following General Procedure A starting from 4-fluoro-3-nitro-benzoic acid (1.0 g) and methylamine (2 M in THF, 8.1 mL) in THF. The crude product was used in the next step without further purification.

後処理

  1. customThe crude product was used in the next step without further purification

出典と根拠

ORDレコード
ord-705eeba1d51b4124a7575f0951cb9830
出典データセット
uspto-grants-2014_06
特許番号
US08759535B2

関連ノート

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