4-Bromobiphenyl → 4-BROMO-4'-SULFOBIPHENYL

HRID 413362ノート

反応式

HRID 413362 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.Cl[S:15]([OH:18])(=[O:17])=[O:16]>C(Cl)(Cl)Cl>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([S:15]([OH:18])(=[O:17])=[O:16])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 71014-BromobiphenylHCID 24638Chlorosulfonic acid

生成物 1

HCID 45247074-BROMO-4'-SULFOBIPHENYL

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

To a solution of 4-bromobiphenyl (18.6 g, 79.8 mmol) in chloroform (150 mL) is added dropwise chlorosulfonic acid (11.2 g, 96 mmol). A white solid precipitate forms during the addition. The reaction is stirred at room temperature for 6 hr, at which time the precipitate is collected by filtration and the precipitate is then washed with cold chloroform. The product is dried under vacuum to give a white solid product. The product is used without further purification.

後処理

  1. additionA white solid precipitate forms during the addition
  2. filtrationis collected by filtration
  3. washthe precipitate is then washed with cold chloroform
  4. customThe product is dried under vacuum
  5. customto give a white solid product
  6. customThe product is used without further purification

出典と根拠

ORDレコード
ord-2c490a80a7fe4849aebeb78957365799
出典データセット
uspto-grants-2003_05
特許番号
US06566381B1

反応ノート

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