Trimethylamine → 1,3-Dihydroxy-5-trimethylsiloxyadamantane

HRID 431418

反応式

HRID 431418 の反応式
[OH:1][C:2]12[CH2:11][C:6]3([OH:12])[CH2:7][CH:8]([CH2:10][C:4]([OH:13])([CH2:5]3)[CH2:3]1)[CH2:9]2.CN(C)C.[CH3:18][Si:19](Cl)([CH3:21])[CH3:20]>C(Cl)Cl>[OH:1][C:2]12[CH2:11][C:6]3([O:12][Si:19]([CH3:21])([CH3:20])[CH3:18])[CH2:7][CH:8]([CH2:10][C:4]([OH:13])([CH2:5]3)[CH2:3]1)[CH2:9]2

参加物

5

反応物 3

HCID 1146TrimethylamineHCID 6397ChlorotrimethylsilaneHCID 98990221,3,5-Adamantanetriol

生成物 1

HCID 219307101,3-Dihydroxy-5-trimethylsiloxyadamantane

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

This 1,3,5-trihydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature. The reaction product was partitioned by high performance liquid chromatography to obtain 1,3-dihydroxy-5-trimethylsiloxyadamantane.

後処理

  1. customReaction
  2. customwas carried out at room temperature
  3. customThe reaction product was partitioned by high performance liquid chromatography

出典と根拠

ORDレコード
ord-609fd757932c4d9781e7d8b82ed4d6a3
出典データセット
uspto-grants-2003_12
特許番号
US06660450B2

関連ノート

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