反応式
[CH3:1][NH:2][C:3]([O:5][N:6]=[C:7]([S:9][CH3:10])[CH3:8])=[O:4].N1C=CC=CC=1.[S:17](Cl)(Cl)=O.[C:21]1([SH:27])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>O1CCCC1>[CH3:1][N:2]([S:27]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[S:17])[C:3]([O:5][N:6]=[C:7]([S:9][CH3:10])[CH3:8])=[O:4]参加物
6
実験手順
A mixture of 3.3 g S-methyl N-[N'-methylcarbamoyloxy]thioacetimidate (0.02 mol), 1.9 g pyridine (0.024 mol) and 2.5 g thionyl chloride (0.021 mol), in 20 ml dry tetrahydrofuran was stirred at room temperature for 4 hours. Pyridine (1.9 g, 0.024 mol) was added and followed by 2.2 g benzenethiol (0.02 mol) added dropwise at water bath temperature. Stirring was continued for an additional hour, and the mixture was worked up as described for Example I. The resulting oily residue was purified by preparative thin-layer chromatography, and the NMR spectrum obtained.
後処理
- additionadded dropwise at water bath temperature
- waitwas continued for an additional hour
- customThe resulting oily residue was purified by preparative thin-layer chromatography
- customthe NMR spectrum obtained
出典と根拠
- ORDレコード
- ord-0618ebcacf30466883b713ededabcaae
- 出典データセット
- uspto-grants-1981_04
- 特許番号
- US04262015
関連ノート
読み込み中…