Ammonia → 2-Amino-1-phenoxy-propene

HRID 476874

反応式

HRID 476874 の反応式
[O:1]([CH2:8][C:9](=O)[CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:12].C1(C)C=CC(S(O)(=O)=O)=CC=1>O1CCCC1>[NH2:12][C:9]([CH3:10])=[CH:8][O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 222AmmoniaHCID 6101p-Toluenesulfonic acidHCID 693131-Phenoxy-2-propanone

生成物 1

HCID 700488602-Amino-1-phenoxy-propene

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

0.2 mol of phenoxyacetone in 200 ml of tetrahydrofuran is saturated at reflux temperature with ammonia gas with the addition of 0.2 g of p-toluene sulphonic acid. The mixture is allowed to stand at room temperature for 24 hours and the solvent is then removed by evaporation in vacuo. The evaporation residue is employed crude in the reaction of Example 5B.

後処理

  1. customthe solvent is then removed by evaporation in vacuo
  2. customin the reaction of Example 5B

出典と根拠

ORDレコード
ord-f9508f221bf3480cacb1d5f539bc49be
出典データセット
uspto-grants-1989_12
特許番号
US04886804

関連ノート

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