Cyproheptadine → 2-[(4-Methylpiperazin-1-yl)methyl]morpholine
反応式
Cl[CH2:2][CH:3]1[O:8][CH2:7][CH2:6][N:5](CC2C=CC=CC=2)[CH2:4]1.[CH3:16][N:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1.CN1CCC(=C2C3C(=CC=CC=3)C=CC3C2=CC=CC=3)CC1>>[CH3:16][N:17]1[CH2:22][CH2:21][N:20]([CH2:2][CH:3]2[O:8][CH2:7][CH2:6][NH:5][CH2:4]2)[CH2:19][CH2:18]1参加物
4
実験手順
By the use of 2-chloromethyl-4-benzylmorpholine and N-methylpiperazine, the reactin is similarly carried out as Reference example 2 to give 2-(4-methyl-1-piperazinylmethyl) morpholine.trihydrochloride as white crystals, melting at 210°-212° C.
出典と根拠
- ORDレコード
- ord-169f0a72445b4186ab52fd476f25a5a6
- 出典データセット
- uspto-grants-1989_12
- 特許番号
- US04889857
反応ノート
読み込み中…