Uridine → 5'-O-(4-Methylbenzoyl)uridine

HRID 48089

反応式

HRID 48089 の反応式
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[C@@H:11]1([N:20]2[CH:27]=[CH:26][C:24](=[O:25])[NH:23][C:21]2=[O:22])[O:19][C@H:16]([CH2:17][OH:18])[C@@H:14]([OH:15])[C@H:12]1[OH:13]>N1C=CC=CC=1>[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([O:18][CH2:17][C@H:16]2[O:19][C@@H:11]([N:20]3[CH:27]=[CH:26][C:24](=[O:25])[NH:23][C:21]3=[O:22])[C@H:12]([OH:13])[C@@H:14]2[OH:15])=[O:7])=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 6029UridineHCID 134054-Methylbenzoyl Chloride

生成物 1

HCID 115885775'-O-(4-Methylbenzoyl)uridine

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

4-Methylbenzoyl chloride (10 mmol) is added to a solution of uridine (10 mmol) in 20 mL of pyridine. After no further progress occurs as observed by TLC, the volatile components are evaporated in vacuo. The residue is purified using flash chromatography to give the product as a colorless oil.

後処理

  1. customthe volatile components are evaporated in vacuo
  2. customThe residue is purified

出典と根拠

ORDレコード
ord-5fea9a53770246ee989f9ac9adc592d9
出典データセット
uspto-grants-2004_03
特許番号
US06702705B1

関連ノート

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