Ethanolamine → Palmitoylethanolamide

HRID 5127

反応式

HRID 5127 の反応式
[NH2:1][CH2:2][CH2:3][OH:4].[C:5](Cl)(=[O:21])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]>C(Cl)(Cl)Cl>[C:5]([NH:1][CH2:2][CH2:3][OH:4])(=[O:21])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

参加物

4

反応物 2

HCID 700EthanolamineHCID 8206Palmitoyl chloride

生成物 1

HCID 4671Palmitoylethanolamide

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

2-Aminoethanol (13.76 g, 225.3 mmol) was dissolved in CHCl3 (750 ml). To the solution was added dropwise palmitoyl chloride (15.48 g, 56.3 mmol) with stirring under ice cooling. Thereafter, the mixture was stirred at room temperature for 19 hours.

後処理

  1. stirringThereafter, the mixture was stirred at room temperature for 19 hours

出典と根拠

ORDレコード
ord-dcadfe0e1eca4e47a8b88dad58fe8309
出典データセット
uspto-grants-1993_09
特許番号
US05243035

関連ノート

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