[NH2:1][C:2]1[C:7]([NH:8][C:9](=[O:18])[O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:6][CH:5]=[CH:4][N+:3]=1[O-].[CH3:20][O:21][C:22]([C:24]#[C:25][C:26]([O:28]C)=O)=[O:23].C1(C)C=CC(S(O)(=O)=[O:37])=CC=1>C(Cl)(Cl)Cl>[CH2:11]([O:10][C:9]([NH:8][C:7]1[C:2]2=[N:1][C:24]([C:22]([O:21][CH3:20])=[O:23])=[C:25]([OH:37])[C:26](=[O:28])[N:3]2[CH:4]=[CH:5][CH:6]=1)=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1To a solution of benzyl (2-amino-1-oxidopyridin-3-yl)carbamate in chloroform (filtered over alumina) was added DMAD and p-toluenesulfonic acid. The suspension was stirred at 70° C. for 12 hours. The solvent was then removed under reduced pressure and to the residue was added MeOH. The solid was filtered, washed with MeOH and dried under vacuum.
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