Acetonitrile → 2-Thenoylacetonitrile
反応式
C(O[C:4]([C:6]1[S:7][CH:8]=[CH:9][CH:10]=1)=[O:5])C.[H-].[Na+].[C:13](#[N:15])[CH3:14]>C1(C)C=CC=CC=1>[S:7]1[CH:8]=[CH:9][CH:10]=[C:6]1[C:4]([CH2:14][C:13]#[N:15])=[O:5]参加物
5
実験手順
78.1 grams (0.5 mole) of thiophene-2-carboxylic acid ethyl ester and 30 grams (1 mole) of sodium hydride (80% suspension in white oil) were reacted with 41.5 grams (1 mole) of acetonitrile in 500 ml of dry toluene. There were obtained 70.0 grams (92.6% of theory) of 2-thiophenoylacetonitrile having a melting point of 110° C.
出典と根拠
- ORDレコード
- ord-6134339ac3da40398099f92e3039b85c
- 出典データセット
- uspto-grants-1988_03
- 特許番号
- US04728743
反応ノート
読み込み中…