Sodium Carbonate → Ethanone, 1-(2-aminophenyl)-, oxime
反応式
[C:1]([C:4]1[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=1[NH2:6])(=O)[CH3:2].Cl.[NH2:12][OH:13].C(=O)([O-])[O-].[Na+].[Na+]>C(O)C>[C:1](=[N:12][OH:13])([C:4]1[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=1[NH2:6])[CH3:2]参加物
5
実験手順
2-Acetylaniline, 33.8 gm, was added slowly to 300 ml of ethanol containing 18.3 gm of hydroxylamine hydrochloride and 27.7 gm sodium carbonate. After addition of the entire amount of 2-acetylaniline, the system was refluxed for 16 hours and then cooled to room temperature. After cooling, the ethanol was removed by stripping. Water was then added to the residue to give a precipitate. The precipitate was filtered and dried to give a pale yellow solid, m.p. 55°-60° C.
後処理
- temperaturethe system was refluxed for 16 hours
- temperatureAfter cooling
- customthe ethanol was removed by stripping
- additionWater was then added to the residue
- customto give a precipitate
- filtrationThe precipitate was filtered
- customdried
- customto give a pale yellow solid, m.p. 55°-60° C.
出典と根拠
- ORDレコード
- ord-7936fbd2671a4dbeac68af9d367419b3
- 出典データセット
- uspto-grants-1988_06
- 特許番号
- US04753943
反応ノート
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