Pyridine → Allyl 2-[4-(2-quinoxalinyloxy)phenoxy]propanoate

HRID 64579

反応式

HRID 64579 の反応式
[CH2:1]([OH:4])[CH:2]=[CH2:3].N1C=CC=CC=1.[N:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:14]=[CH:13][C:12]=1[O:21][C:22]1[CH:33]=[CH:32][C:25]([O:26][CH:27]([CH3:31])[C:28](Cl)=[O:29])=[CH:24][CH:23]=1>C(Cl)Cl>[N:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:14]=[CH:13][C:12]=1[O:21][C:22]1[CH:33]=[CH:32][C:25]([O:26][CH:27]([CH3:31])[C:28]([O:4][CH2:1][CH:2]=[CH2:3])=[O:29])=[CH:24][CH:23]=1

参加物

5

反応物 3

HCID 1049PyridineHCID 7858Allyl AlcoholHCID 136705322-[4-(2-Quinoxalinyloxy)phenoxy]propionyl chloride

生成物 1

HCID 13670534Allyl 2-[4-(2-quinoxalinyloxy)phenoxy]propanoate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

To a solution of 1.2 g allyl alcohol and 1.6 g pyridine in 50 cc methylene chloride, add 6.6 g of 2-[4-(2-quinoxalinyloxy)phenoxy]propionyl chloride in 60 cc methylene chloride. Stir the mixture at room temperature overnight. Wash the methylene chloride solution with water and dry the solution over magnesium sulfate concentrate under vacuum to give allyl 2-[4-(2-quinoxalinyloxy)phenoxy]propanoate.

後処理

  1. washWash the methylene chloride solution with water
  2. dry with materialdry the solution over magnesium sulfate
  3. concentrationconcentrate under vacuum

出典と根拠

ORDレコード
ord-a9135ae31a7f4357adf017005813a8cd
出典データセット
uspto-grants-1986_09
特許番号
US04609396

関連ノート

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