5'-Atp → L-Tryptophan

HRID 655094

反応式

HRID 655094 の反応式
[CH2:1](OP(O)(O)=O)[C@H:2]1O[C@H:5](OP(OP(O)(O)=O)(O)=O)[C@H:4](O)[C@@H:3]1O.P(OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](O)[C@@H]1O)(OP(OP(O)(O)=O)(O)=O)(=O)O.[NH2:54][C@H:55]([C:62]([OH:64])=[O:63])[CH2:56][C:57]1N=[CH:60][NH:59][CH:58]=1>>[NH2:54][C@H:55]([C:62]([OH:64])=[O:63])[CH2:56][C:57]1[C:5]2[C:60](=[CH:1][CH:2]=[CH:3][CH:4]=2)[NH:59][CH:58]=1

参加物

4

反応物 3

HCID 59575'-Atp2 回HCID 7339Phosphoribosyl Pyrophosphate2 回HCID 178419078HCID 178419078、化合物2 回

生成物 1

HCID 6305L-Tryptophan

実験手順

5-Phosphoribosyl-α-1-pyrophosphate (hereinafter, “PRPP”) and adenosine-5′-triphosphate (hereinafter, “ATP”) are the initial substrates in histidine biosynthesis. PRPP can sometimes induce the histidine biosynthesis to follow divergent pathways, resulting in the biosynthesis of pyrimidine nucleotides, purine nucleotides, pyridine nucleotides, and tryptophan (Escherichia coli and Salmonella, Second Edition, Editor in Chief: F. C. Neidhardt, ASM Press, Washington D.C., 1996).

出典と根拠

ORDレコード
ord-8a93aaca8cfb4bda82219c51c57b8cd5
出典データセット
uspto-grants-2011_12
特許番号
US08071339B2

関連ノート

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