反応式
[N-:1]=[N+:2]=[N-:3].[Na+].[Cl:5][CH2:6][C:7]([CH3:12])([CH3:11])[C:8](Cl)=[O:9].C(OC(=O)C)C>O1CCOCC1.O.CCCCCC>[Cl:5][CH2:6][C:7]([CH3:12])([CH3:11])[C:8]([N:1]=[N+:2]=[N-:3])=[O:9]参加物
7
実験手順
Sodium azide (4.64 g, 71.38 mmol) was added to a solution of 3-chloro-2,2-dimethyl-propionyl chloride (I-200a: 6 g, 35.71 mmol) in 1,4-dioxane (15 mL) and water (15 mL). The resulting mixture was stirred at room temperature for 2 hours. The reaction was monitored by TLC (5% ethylacetate in hexane). The reaction mixture was extracted with diethyl ether and the organic layer was dried over Na2SO4 to afford 3.5 g of the product (61.40% yield).
後処理
- extractionThe reaction mixture was extracted with diethyl ether
- dry with materialthe organic layer was dried over Na2SO4
出典と根拠
- ORDレコード
- ord-61aeecbee34f43d2baa40b2c427cbaf5
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- USRE045173E1
関連ノート
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