Desipramine Hydrochloride → Desipramine
反応式
[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][N:6]1[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[CH2:14][CH2:13][C:12]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]1=2.Cl>[OH-].[Na+]>[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][N:6]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:12]=2[CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]1=2参加物
3
実験手順
To 6.02 g of desipramine hydrochloride was added 150 ml of 1N NaOH. The mixture was allowed to stir for 10 minutes. The aqueous mixture was extracted with 6×100 ml of chloroform. The combined chloroform layer was washed with 200 ml of water. The organic part was dried (Na2SO4) and concentrated to give 5.25 g of desipramine free base.
後処理
- extractionThe aqueous mixture was extracted with 6×100 ml of chloroform
- washThe combined chloroform layer was washed with 200 ml of water
- dry with materialThe organic part was dried (Na2SO4)
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-78cbff80e04c44a7a384b30c58aff007
- 出典データセット
- uspto-grants-2002_04
- 特許番号
- US06368814B1
反応ノート
読み込み中…