Methyl iodide → Quinoline
反応式
C(=O)([O-])[O-].[K+].[K+].[Na].[H][H].CI.C(I)CC.[CH2:16](I)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[CH2:24]([N:26](CC)CC)[CH3:25]>>[N:26]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:25][CH:24]=1参加物
7
実験手順
To the solution is added one equivalent to a small excess amount of a base, e.g. potassium carbonate, triethylamine, sodium hydrogen, one equivalent to excess amount of halogens alkyl derivative, e.g. methyl iodide, propyl iodide, benzyl iodide, and the mixture is stirred at a temperature of 0° C. to 80° C. to give a quinoline derivative (ivz).
出典と根拠
- ORDレコード
- ord-fca95870832c4d87b38e4a935aee1564
- 出典データセット
- uspto-grants-2000_01
- 特許番号
- US06015789
反応ノート
読み込み中…