Sulfuric Acid → Dimedone
反応式
[O:1]=[C:2]([CH3:11])[CH2:3][C:4]([CH3:10])([CH3:9])[CH2:5][C:6](O)=[O:7].S(=O)(=O)(O)O>C(Cl)(Cl)Cl>[CH3:9][C:4]1([CH3:10])[CH2:3][C:2](=[O:1])[CH2:11][C:6](=[O:7])[CH2:5]1参加物
4
実験手順
A solution of 5 parts of 5-keto-3,3-dimethylhexanoic acid and about 15 parts of 73% sulfuric acid was heated for one hour in a 130°-135° oil bath. The cooled solution was then poured into a separatory funnel containing ice and chloroform. The aqueous phase was then washed three times with additional chloroform. The combined organic extractions were then dried and evaporated. There was obtained an 82.3% yield of dimedone. It was further recrystallized from toluene.
後処理
- additionThe cooled solution was then poured into a separatory funnel
- washThe aqueous phase was then washed three times with additional chloroform
- extractionThe combined organic extractions
- customwere then dried
- customevaporated
出典と根拠
- ORDレコード
- ord-d7eca5d1c32145dd995fe32b68df792d
- 出典データセット
- uspto-grants-1983_05
- 特許番号
- US04386222
反応ノート
読み込み中…