Water → HCID 70145705、化合物

HRID 865160ノート

反応式

HRID 865160 の反応式
[CH2:1]([OH:6])/[CH:2]=[CH:3]\[CH2:4][CH3:5].[H-].[Na+].Cl[C:10]1[C:14]([C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[N:13][S:12][N:11]=1.O>O1CCCC1>[CH2:1]([O:6][C:10]1[C:14]([C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[N:13][S:12][N:11]=1)/[CH:2]=[CH:3]\[CH2:4][CH3:5]

参加物

6

反応物 4

HCID 962WaterHCID 24758Sodium hydrideHCID 5364919cis-Pent-2-ene-1-olHCID 104881643-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole

生成物 1

HCID 70145705HCID 70145705、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

To a solution of cis-2-penten-1-ol (780 mg, 9 mmol) and sodium hydride (310 mg, 9 mmol) in dry tetrahydrofuran was added a solution of 3-(3-chloro-1,2,5-thiadiazol-4-yl)pyridine (590 mg, 3 mmol) in dry tetrahydrofuran. The reaction mixture was stirred at room temperature for 1 h. Water was added and the mixture was extracted with ether. The ether phase was dried and evaporated to give the title compound.

後処理

  1. extractionthe mixture was extracted with ether
  2. dry with materialThe ether phase was dried
  3. customevaporated

出典と根拠

ORDレコード
ord-27cc7c20447b4c5f9a8b88a8993a9220
出典データセット
uspto-grants-1996_10
特許番号
US05565475

反応ノート

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